Picture of Jerome Canivet

Jerome Canivet

Researcher

Orcid number: 0000-0002-0458-3085


445 424 (Switchboard + 33 [0] 472 445 300)
P105

Keywords

Molecular Catalysis, Metal-Organic Frameworks (MOF), Porous Organic Polymers (POP), Covalent Organic Frameworks (COF), Covalent Triazine Frameworks (CTF), Post-Synthetic Functionnalization, Confinement, Fine Chemicals, Photocatalysis, Carbon Dioxide (CO2), Asymmetry, Chirality, Macroligand

Molecular Hybrid Catalysts for Fine Chemicals Synthesis and Clean Energy Production
 

Jérôme Canivet was appointed CNRS researcher at the IRCELYON in 2010.
Within the ING group of IRCELYON, his "MOF team" accounts for 7 PhD students, postdocs and engineer and collaborates tightly with other CNRS permanent researchers in Lyon (DNP SENS), Lille (time-resolved spectroscopy) and Paris (computational chemistry).
His team develop new catalytic systems answering current challenges in fine chemicals synthesis and clean energy production by unravelling novel molecular catalysts and heterogenizing within Porous Macroligands, a concept he established for synergistically bridging homogeneous and heterogenous catalysis.
The "MOF team" research efforts are mainly funded by H2020 and ANR programs with projects going from TRL3 to TRL 5/6.
In 2018, he received the Young Investigator Award from the Catalysis Division of the French Chemical Society for creating trends reducing the gap between homogeneous and heterogeneous catalysis.
He further aims at exploiting the confinement of molecular catalytic systems into porous structures for the improvement of their catalytic activity and selectivity, and he is coordinating cooperative projects on this topic.

 

Career

2010- now: Permanent CNRS researcher at IRCELYON, France.
Principal Investigator on molecular hybrid materials for fine chemical synthesis and photocatalysis

2009-2011: Postdoctoral research project done at the CNRS with Dr. David Farrusseng, Metal-organic frameworks from sorption to catalysis, IRCELYON, France.

2007-2009: Postdoctoral research project done at the Noyori’s Laboratory under the direction of the Prof. Kenichiro Itami, Catalyzed direct CH arylation, University of Nagoya, Japan.

2003-2007: Ph.D research project done at the Laboratory of Organometallic Chemistry and Molecular Catalysis directed by the Prof. Georg Süss-Fink, Synthesis of water-soluble arene ruthenium, rhodium and iridium complexes and study of their catalytic potential for the transfer hydrogenation reaction in aqueous solution, Chemistry Institute of Neuchâtel, Switzerland.
 

Education

University of Lyon (France): Professorial Thesis (Habilitation à Diriger des Recherches), 2017
University of Neuchâtel (Switzerland): Ph. D., Organometallic Synthesis and Molecular Catalysis, 2007
University of Lille (France): M. S., Organic and Macromolecular Chemistry, 2003
University of Lille (France): B. S., Physical and Chemical Sciences, 2001
 

Awards

2020: Green Chemistry Emerging Investigator, RSC
2019: CNRS research award for outstanding scientific contribution
2019: Emergence@International travel grant from Institute of Chemistry - CNRS (Japan lecture tour)
2018: Young Researcher Award from the Catalysis Division of the French Chemcial Society (DivCat)
2007: SNF Postdoctoral Fellowship for Prospective Researchers, Swiss National Science Foundation (supported by Prof. J.-E. Bäckvall, Stockholm University, Sweden).
2007: JSPS Postdoctoral Fellowship for Foreign Researchers, Japan Society for the Promotion of Science (supported by Prof. K. Itami, Nagoya University, Japan).
 

Research impact

as in Scopus on August 2020: 47 scientific papers (J.Am.Chem.Soc.,  Angew. Chem., Chem. Sci., ACS Catal., Green Chem... ), H index = 24, > 350 citations/year
3 book chapters
5 patents

more than 40 lectures in international conferences including 10 invitations since 2010

 

Coordinator of the French ANR project PoMAC: Confinement of peptide sequences in Porous Macroligand for Asymmetric Catalysis see also the project page

 

Coordinator for CNRS of the H2020 project H-CCAT: Solid Catalysts for activation of aromatic C-H bonds see also the project page

 

for updated scientific production see

HAL - open archive

ORCID

Scopus

Follow us on Twitter  MOF@IRCELYON
 

From Homogeneous to Heterogeneous Catalysis for Sustainable Chemical Processes

 

Environmentally friendly and cost efficient processes attract continuously growing interest for applications in catalysis and organic synthesis.

The main aim of my PhD work (2003-2007), in the Süss-Fink group at Neuchâtel University, Switzerland, was to develop efficient catalysts in aqueous solution, especially for transfer hydrogenation of ketones and imines to give an environmentally friendly access to alkaloids via asymmetric catalysis in water.

NADH


In this “green chemistry” concept, I extended my field of research to other catalytic reactions like carbon-carbon coupling and to self-assembled materials. Thus I joint the Itami group (2007-2009), first as a part of the Noyori Laboratory, in Nagoya, Japan, as a JSPS postdoctoral fellow in order to develop new systems (molecular catalysts and/or nanoparticles) able to catalyze the heteroarenes functionalization (via CH activation) under mild conditions, enhancing the cost efficiency of the process.

coupling 

Since 2009, I joint the group of Engineering and Process Intensification at the CNRS in the Institute of Researches on Catalysis en Environment of Lyon (IRCELYON) in order to develop new catalysts based on the MOFs technology, expanding the field of applications of these promising porous crystalline materials. I therefore developed new catalytic species confined into the MOFs cavities in order to obtain innovative selectivities with heterogeneized molecular catalysts.

MOF_cat
 

I developed the concept of solid macroligand, using MOF and microporous polymers as valuable representatives. We show that polymer-based macroligands allow designing heterogeneous catalysts with similar versatility than found in molecular chemistry and homogeneous catalysis.

Our main finding is that the Hammett parameter is a performing descriptor of all the active sites, irrespective of their nature (heterogeneous or molecular) and the Hammett parameter can be directly linked to the catalytic performance of the catalysts with no gap between homogeneous and heterogeneous catalysis. While the usefulness of the Hammett parameter is well established in molecular chemistry, no such evidence was present for heterogeneous/heterogenized catalysts so far. This perfect correlation has been established for Rh-based catalytic systems in both CO2 photoreduction (ACS Catal. 2018) and ketones transfer hydrogenation (ChemCatChem 2018).

The established correlation between the catalytic activity and the Hammett parameter highlights the crucial impact of the local electronic environment surrounding the active catalytic center over the long-range framework structure, as demonstrated for two different MOF and four CMP-based catalysts. The general linear trend gives also insight into the contribution of the diffusion limitation inside the porous network of such heterogeneous catalysts or of unexpected reactivity of functional groups at the macroligand.

This opens new perspectives for the rational design of efficient heterogeneous catalysts based on molecular species.

Both MOF and Microporous Polymers thus appear as very appealing platforms and their use as macroligands for the heterogenization of molecular catalysts is further reducing the gap between homogeneous and heterogeneous catalysis.

Fine chemicals synthesis and clean energy production

Jérôme  Canivet's team develop new catalytic systems answering current challenges in fine chemicals synthesis and clean energy production by unravelling novel molecular catalysts and heterogenizing within Porous Macroligands, a concept we established for synergistically bridging homogeneous and heterogenous catalysis.

 

Molecular Catalysts Confined inside Cavities: The Concept of Solid Porous Macroligands

Thanks to their hybrid formulation, Metal-Organic Frameworks (MOF) shall bridge the gap between pure inorganic and organic materials, thereby pushing the frontiers of knowledge ever further. Initially, MOFs were regarded only as a new type of molecular sieve material with a pore size between those of inorganic zeolites (<1 nm) and ordered mesoporous silica materials (>2 nm). On the other hand, their stimuli-induced flexibility, or more generally their softness, is common trait with organic enzymes.  Novel porous platforms allows adressing new challenges in heterogeneous catalysis whicle tackling issues on stability and control over active site: Covalent Organic Frameworks (COF) and Conjugated Microporous Polymers (CMP).
From MOF to COF and CMP, they present decreasing ordered structure and control over the porosity but increasing chemical stability.

They thus appear as very appealing platforms and their use as macroligands for the heterogenization of molecular catalysts is further reducing the gap between homogeneous and heterogeneous catalysis.


Research topics range from C-C coupling to asymmetry, photocatalysis and green fuels.

 

---------- Funding scheme: national and international collaborative projects -----------------

Jérôme Canivet further aims at exploiting the confinement of molecular catalytic systems into porous structures for the improvement of their catalytic activity and selectivity, and he is coordinating cooperative projects on this topic.


-> Coordinator of the ANR PoMAc project (2018-2022, 42+6 months,  385 k€)
"Confinement of peptide sequences in Porous Macroligand for Asymmetric Catalysis"
(noble metal-based chiral porous catalysts) TRL3


-> WP leader - partner scientific coordinator of the H2020 H-CCAT project (2017-2021, 48+6 months, 12 partners, 7.6 M€) http://h-ccat.eu/
"Solid Catalysts for activation of aromatic C-H bonds"
(hybrid heterogeneous catalysts for C-H arylation) TRL3 -> TRL5
 

-> Partner of the H2020 C123 project (2019-2023, 48 months, 13 partners, 6.3 M€)
"Methane oxidative conversion and hydroformylation to propylen"
(hybrid heterogeneous catalysts for hydroformylation) TRL3 -> TRL5


-> Partner of the ANR Cat2Cat project (2016-2020, 42+6 months,  575 k€)
"From catalysts to cathodes: a controlled-architecture approach for PEMFC electrodes catalyzed by Earth-abundant metals"
(doped-MOF precursors to catalytic carbon electrodes) TRL3/4

 

---------- MOF Team members ---------------

PhD students


Alisa Ranscht (started 06/2020) – Porous electrocatalyst for small molecules activation (Indust. Funding)


Baptiste Chauchon (started 10/2018) – Porous catalysts for asymmetric transfer hydrogenation (ANR)


Remy Rajapaksha (started 10/2018) – Porous catalysts for alkenes oligomerization (Univ. Lyon grant)


Hua Wei (started 11/2017) – Doped MOF layers for catalysis (SINCHEM program)


Clement Demarcy, 02/2017 – 10/2020, Synthesis of homogeneous and supported Pd(NHC) catalysts for the selective arylation of indole at the C-3 position (H2020 program, Univ. Lyon 1)


Marcelo Alves-Favaro, 05/2017 – 05/2020,  Synthesis of new Covalent Triazine Frameworks for Carbon Dioxide Photoreduction (EU-SINCHEM program, Univ. Lyon 1 – RWTH Aachen)


Yorck Mohr, 02/2017 – 04/2020,  From Molecular Catalysts to their Incorporation in Porous Materials: The Case of Regiospecific Aromatic CH Arylation (H2020 program, Univ. Lyon 1)


Jonathan Bonnefoy, 10/2012 – 10/2015, Conception of new bio-inspired MOF-based hybrid materials with advanced functionalities for catalysis (ANR program, Univ. Lyon 1)


Postdoctoral collaborators

Dr. P. Samanta                   Nov. 2020 –                 (H2020)

Dr. M. Alves-Favaro         May. 2020 –                (H2020)

Dr. A. Ghosh                      Sept. 2019 –                (CNRS)           

Dr. Y. Roux                       Jun. 2018 – May. 2020 (H2020)

Dr. K. Barbera                   Jan. 2017 – Jan. 2019 (ANR)

Dr. E. Bernoud                   Sept. 2016 – Sept. 2017(Univ. Lyon)

Dr. F. M. Wisser                Apr. 2016 – Jan. 2020 (DFG grant, Germany; CNRS)

Dr. M. Vandichel               Jun. 2015 – Dec.2015 (invited researcher from UGhent, Belgium)

Dr. A. Legrand                  Oct. 2013 – Jan.2016       (ANR)

 

Undergraduate students

2020           P. Bredy (CPE Lyon)

2019          A. Ranscht (Uni. Leipzig)

2019           L. Grousset (Univ. Montpellier)

2018           F. Tamisier (Univ. Grenoble)

2017           S. Abou-derhamine (Univ. Lyon)

2017           M. Balas (CPE Lyon)

2016           M. Tripathi (Univ. Grenoble)

2016           H. Hussein (Univ. Lyon)

2015           A. Valette (UPMC, Paris)

2015           B. Mortada (Univ. Lyon)

2014           S. Leinardi (Univ. Lyon)

2013           A. Molino (Univ. Torino)

 

 

Follow us on Twitter  MOF@IRCELYON
 

Heterogenization of Active Molecular Catalysts within Solid Porous Macroligands

ChemCatChem 2020, 12, 1270-1275

 

 

For Photocatalysis and Solar Fuels

see ACS Catal. 2018, 8, 1653-1661
       Angew. Chem. Int. Ed. 2020, 59, 5116-5122

 

 

For Sustainable Asymmetric Catalysis 

Abstract Image

see J. Am. Chem. Soc. 2015, 137, 9409-9416
       Chem. Sci. 2020, 11, 8800-8808

 

 

For Understanding Host-Guest interactions using DFT combined with DNP-SENS

see Chem.Eur.J. 2016, 46, 16531-16538

 

 

For Ethylene Valorization Processes

Ni_oligom2
 see J. Am. Chem. Soc. 2013, 135, 4195-4198

 

 

Advanced lectures for graduated students

2019: ITbm/GTR Seminar Series, Nagoya, Japan
Heterogenized molecular catalysis: Unifying two world

2019: Elicat Summer School on Catalysis, Villeurbanne, France
Application of Metal-Organic Frameworks to Catalysis

2017: Elicat Summer School on Catalysis, Villeurbanne, France
Metal-Organic Frameworks: Extended Molecular Networks vs. Surface Science

2014: IGER/ITbM/RCMS Seminar Series, Nagoya, Japan
Metal-Organic Frameworks: A new tale of the Emperor's new clothes